UROP Proceedings 2021-22

School of Engineering Department of Chemical and Biological Engineering 79 Humanitarian Chemical Engineering - A Summer Expedition Supervisor: MAK Andrew T C / CBE Student: HUI Yanna Yatnga / BIEN Course: UROP1000, Summer Malaria, a fatal disease caused by parasites, has put half of the world’s population at risk. Together with the continuous ENGG 4930E SIGHT project of Myanmar Malaria, this UROP 1000 project focuses on humanitarian engineering solutions on Malaria Control, not only Myanmar but globally available approaches. Knowing that the focus of humanitarian engineering is to serve a highly effective solution at a low cost to suit everyone in need, a total of three approaches as options at different stages during design thinking have been proposed. Including the Water Recycle Robot, Water Source Improvements, and Bacteriophage approaches. The purpose of these approaches are all to eliminate Malaria at root for the highest effectiveness and alleviate its harm to human beings. These solutions are compared and analysed under cost, possibility of implementation, and effectiveness, with a final decision of focusing on developing the idea of Water Recycle Robot. Neural Circuits for Visual Behaviors in Zebrafish Supervisor: SEMMELHACK Julia Lee / CBE Student: ZHAO Yicheng / BCB Course: UROP1100, Summer Behavior studies are crucial for research about the brain, here we used zebrafish as a model to study an important part of its hunting behavior, strike. Prey captures of a zebrafish consist of 3 steps, J-turns, approaches, and capture strikes. Strike is the last step of prey capture, and usually appears when a strong prey capture occurs (typically characterized by strong J turns, i.e. the bend of the larvae tail). To simulate the prey, we used an LCD screen to present the larvae with a moving dot. We tested 3 different types of dots, sweeping dots, stationary dots, and flickering dots respectively; the size of which was also tested to find the ideal condition for triggering prey capture and strike. We found that a 4-degree dot is optimal to trigger both prey capture and strike, and a sweeping dot is more effective in inducing behaviors than stationary and flickering dots. Figure 1: Strike of an embedded fish vs a free swimming fish