UROP Proceedings 2021-22

School of Engineering Department of Chemical and Biological Engineering 84 Analyzing the Possible Water-Soluble Proteins for Deep-Tissue and Cancer-targeting in Vivo Imaging Using a Photoacoustic Imaging System Supervisor: WONG Tsz Wai / CBE Student: LAI Ka Wai / BIEN Course: UROP2100, Summer The objective of this project is to develop a biodegradable contrast agent for a deep-tissue photoacoustic imaging system which can potentially overcome various limitations in other existing imaging modalities and generate images with higher qualities. This system requires a contrast agent that is biodegradable, non-toxic, has a near-infra-red absorption peak, a high extinction coefficient, and a low quantum yield. A potential candidate for such a contrast agent is composed of water-soluble chlorophyll-binding proteins, SpyTag and SpyCatcher proteins, and human epidermal receptor 2 affibodies. Traditionally, chlorophylls are used as the central phytochrome binding to the protein. However, in this experiment, LvPCPS was combined with bacteriochlorophyll A for the formation of the contrast agent. It was found that bacteriochlorophyll is a suitable alternative to chlorophyll from plants for the contrast agent. Mask but Not the Least Supervisor: YEUNG King Lun / CBE Student: CHEUNG Howard Yau Ming / CIEV KANDWAL Inika / EVMT LIEM Albert / SUSEE Course: UROP1100, Fall UROP1100, Fall UROP3100, Fall The COVID-19 pandemic has not only affected and hindered our daily lives, or the environment today, but has asked us to seriously consider the environmental impacts of our lifestyle choices. A prominent issue at the moment is the unattended disposal of face masks, around 129 billion face masks every month. This paper explores the creation of composite prototypes using shredded mask waste and other waste materials (paper, natural fibres etc) to create load-bearing, water resistant and aesthetic material. We aim to create products of high-value and function as well as using them to raise awareness around the importance of proper mask disposal.